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Dogs + Medications & Supplements

  • Sildenafil is given by mouth or injection and is used off label to treat high blood pressure in the lungs or to treat megaesophagus. Give as directed. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, or skin redness in the groin area. Do not use in pets that are allergic to it or pets that take nitrate medications. If a negative reaction occurs, please call your veterinarian.

  • Silver sulfadiazine topical is an antimicrobial used to treat skin infections and burns in cats, dogs, and exotic pets. It is used off label in veterinary medicine. Silver sulfadiazine topical comes in a topical cream.

  • Slippery elm is given by mouth and is used over the counter to treat cough and stomach upset in dogs and cats. Give as directed by your veterinarian.

  • Smectite (Bio-Sponge®) is an intestinal support supplement used in various animal species, including dogs, cats, horses, cattle, and small ruminants. It has adsorbent properties may help bind toxins, bacteria, viruses, and free-radicals in the intestinal tract.

  • Sodium chloride (hypertonic) ophthalmic is a topical medication used to reduce surface (corneal) swelling of the eye in cats and dogs. Sodium chloride is available without a prescription but should only be used under the direction of a veterinarian. It may be used “off label” or “extra label” to treat eye conditions in animals other than cats or dogs. Sodium chloride (hypertonic) ophthalmic comes in ointment and liquid drop form. Avoid use in animals with corneal ulceration or dry eye.

  • Sotalol is given by mouth or injection and is used off label in dogs and cats to treat abnormal heart rhythms. The most common side effect is tiredness.

  • Soy protein is given by mouth and is used over the counter to treat many conditions such as urinary incontinence, certain cancers, inflammation, obesity, and diabetes. Side effects may include gastrointestinal signs, or allergic reactions. Do not use in pets that are allergic to it, or in pets that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.

  • Spinosad (brand name Comfortis®) is an antiparasitic used to kill adult fleas and to prevent and treat flea infestations in dogs and cats. It may be used off label (extra label) to treat other parasites and in other animals. It comes in an oral tablet form.

  • Spironolactone is given by mouth and is used off label to treat congestive heart failure, fluid accumulation, and other cardiovascular problems.

  • Spironolactone + benazepril (brand name Cardalis®) is a combination aldosterone antagonist (spironolactone) and angiotensin-converting enzyme inhibitor or ACE inhibitor (benazepril) used to treat certain types of congestive heart failure in dogs. Use to treat other heart conditions or in other species is "off label" or "extra label". Spironolactone + benazepril comes in chewable meat-flavored tablet form.

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